Thursday, April 28, 2011

Rheumatic fever symptoms - Leptospirosis -Listeria symptoms

SYSTEMIC / MULTISYSTEM INFECTIONS 


RHEUMATIC FEVER 

Rheumatic fever is an inflammatory disease that can develop after an infection with Streptococcus bacteria (such as strep throat and scarlet fever) and can involve the heart (especially the valves), joints, skin and brain. Rare in developed countries like Great Britain, USA and Australia. Incidence has dropped by 10% of children in 1920 to 0.01% of all children today. This reduction in the incidence reflect advances in infection control and treatment of streptococcal infections to antimicrobials. The disease is still prevalent in developing countries such as the Middle and Far East and Latin America.

Rheumatic fever is preceded by a throat infection with Streptococcus organsisms. After infection with group A streptococcal pharyngeal, usually in childhood (5-15And) is followed by a systemic syndrome I think it is caused by an autoimmune reaction triggered by an infection. Syndrome includes: 1) Arthritis (multiple join pain and swelling) 2), carditis (heart inflammation) 3) The cutaneous manifestations 4) manifestations5 nervous system), fever, joint pain 50% etc.About Patients who develop carditis during the initial phase of the disease will continue to develop long-term heart disease and rheumatic valvular disease.





1) Blood tests: ESF and CRP (non-specific inflammation), leukocytosis2) Studies in X-ray may be a sign of heart infection, pericarditis, pericardial effusion effusion.3) ECG may signs of inflammation of the heart (extended range PR) or, and pericarditis (saddle-shaped ST elevation). Parts of the acute clinical syndrome may recur after the first period. However, projected common disease, skin disease and nerve disease associated with rheumatic fever is excellent with no known long-term consequences. rheumatic heart disease has traditionally been hailed as an important causal factor of cardiac valvular disease and makes the associated morbidity and mortality.


LEPTOSPIROSIS 

Leptospirosis is a rare infection, serious and contagious caused by bacteria of several species of the genus Leptospira, a micro-organism spiral (spirochete). Leptospirosis is often called the swineherd's disease, swamp fever, or mud fever. The organism enters the body when mucous membranes or abraded skin comes into contact with contaminated environmental sources. The infection causes a systemic disease that can often lead to renal and hepatic failure as possible. 

 Leptospirosis is a zoonosis (animal care) infection with a worldwide distribution and incidence. The incidence varies from sporadic in temperate zones endemic in some tropical countries. The disease has a seasonal incidence. Most cases occur during the rainy season in the tropics and in western countries in late summer or early fall, when soil is moist and alkaline. Leptospirosis is usually associated with tropical countries and heavy rains, but most cases occur in temperate climates, probably due to underreporting in some countries.





In general, the prognosis associated with this disease is good, usually with full recovery after infection. more serious systemic infections (Weil's disease), can lead to renal (kidney) or hepatic (liver), myocarditis (heart inflammation), and can be potentially fatal.
Approximately 15-40% of patients are exposed, but do not become ill show serologic (blood or urine or saliva) evidence of a past existing infection. This statistic includes 15% of abattoir workers, home workers, and the incubation period is usually between 7-12 days veterinarians.The, with a range of 2-20 days. About 90% of patients experience a mild form of the disease,
and about 5-10% have the severe form with jaundice, also known as Weil's disease. The natural course of leptospirosis is divided into two very distinct phases, sepsis and immune systems. For a brief period of 1-3 days between the first and second phase, the patient shows some improvement.


LISTERIOSIS 

Listeriosis is an infectious disease caused by foodborne bacteria Listeria monocytogenes. The symptoms are the symptoms of upper respiratory tract and septiceamia. Listeriosis is of particular concern during pregnancy because it can cause miscarriage, stillbirth, premature delivery and sepsis (full body infection) and pneumonia in newborns.

It is an environmental organization that is ubiquitous in soil and rotting matter.It affect both animals and humans, the most common way of infection to humans in contaminated food. The organism can grow at temerature as low as 4 degrees Celsius, and the foods most frequently implicated are soft cheeses, unpasteurized, raw vegetables and the chicken heads. Listeriosis is a rare but serious infection that mostly affects infants, pregnant women, elderly and immunocompromised, L. monocytogenes has also been recently recognized as a cause of self-limiting gastroenteritis, foodborne healthy adults, but the incidence of this phenomenon is unknown....... read more





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